NAD is a coenzyme found in all living cells. It plays a crucial role in cellular metabolism, especially in processes like energy production and DNA repair. NAD exists in two forms:
NAD+ (oxidised form) – Acts as a carrier for electrons in metabolic reactions. It is essential for converting nutrients into energy by facilitating reactions in cellular respiration, especially in the Krebs cycle and the electron transport chain.
NADH (reduced form) – This form donates electrons during various biochemical processes, particularly in ATP (energy) production.
NAD is also involved in the regulation of sirtuins, enzymes that play a role in aging, inflammation, and stress resistance. NAD+ has gained attention for its potential in anti-aging therapies and enhancing mitochondrial function.
What we test
NAD
NAD does not occur directly in food. However, the building blocks for NAD, which are vitamins and amino acids, can be found in various foods. These building blocks are then absorbed by the body and converted into NAD through metabolic processes.
NAD+ is a coenzyme essential for energy production in the mitochondria. It plays a pivotal role in converting nutrients into energy (ATP).
NADH is the reduced form of NAD+ and is equally vital in energy metabolism. A healthy balance between NAD+ and NADH is crucial and influences everything from energy levels to immune function.
NADPH plays a critical role in anabolic reactions, including lipid synthesis, antioxidant defence, and detoxification. It helps combat oxidative stress, protecting cells from damage and supporting immune health.
NADP is the oxidized form of NADPH and is involved in various biosynthetic pathways, including fatty acid and cholesterol synthesis, and is essential for tissue repair and regeneration.
Nicotinamide, also known as niacinamide, is a form of vitamin B3 that serves as a precursor to NAD+. It has been shown to support healthy skin, reduce inflammation, and promote cellular repair.
Nicotinic acid, another form of vitamin B3, also contributes to the synthesis of NAD+ in the body. Proper nicotinic acid levels are key for maintaining a healthy lipid profile, cardiovascular health, and energy balance.
The NAD+/NADH ratio is a key indicator of the balance between oxidation and reduction processes within cells.
This ratio reflects the balance between oxidative and reductive processes within cells. A balanced NADP/NADPH ratio is essential for efficient detoxification, antioxidant defence, and protection against oxidative damage.
The NAD/NADP index provides an overview of the overall balance between the NAD and NADP pathways. This index can be used to evaluate the body's ability to manage oxidative stress, regulate energy production, and support cellular repair mechanisms.
Test instructions
Your test kit and all instructions are posted directly to you, and there is no need to visit a collection centre.
This test requires a finger-prick blood test included in your kit.
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