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Markers of bowel inflammation

The symptoms of Irritable Bowel Syndrome (IBS) and Inflammatory Bowel Disease (IBD) can be very similar but they are two very different medical conditions. Historically gastroenterologists have had to use endoscopies to distinguish between the two disorders. Calprotectin tests are used to detect inflammation in the gut which may be caused by Inflammatory Bowel Disease such as Crohn's or ulcerative colitis, and thus can help distinguish between these conditions.

What we test

Calprotectin

Calprotectin is a protein released by a type of white blood cell. When there is inflammation in the gastrointestinal tract, white blood cells move to the area and release calprotectin, resulting in an increased level in the stool.

This stool test measures:

This protein is released into the stool when the intestinal lining is damaged. It's usually very high in cases of Inflammatory Bowel Disease (such as Crohn's or ulcerative colitis), and low in IBS. Calprotectin is also elevated with gut infections and colon cancers.

A value above 150 mcg/g indicates significant inflammation in the gastrointestinal tract and an endoscopy or colonoscopy should be considered where the source of inflammation is not clear.

Test instructions

Your test kit and all instructions are posted directly to you, and there is no need to visit a collection centre.

Mail your sample back to the lab according to the instructions provided with your kit

Results for this test available in 2-4 weeks depending on region and will be published in your online dashboard.

Ready. Set. Go!
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